I'm definitely interested in learning more about biohacking.
I have some experience growing cultures and even growing edible mushrooms from both spores and dikaryotic mycelia. Back when I used to play with this, I put together a positive flow hood using a plastic enclosure, an old PC power supply, and a HEPA filter. It wasn't perfect, but for transferring mycelia -- which have some resistance to bacterial infections -- it worked quite well. I used a pressure canner as an autoclave, which did a fairly decent job.
Another possibility for biohacking, assuming that there are beer / wine brewers here, is keeping, purifying, and maintaining yeast lines.